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PurO3 Probiotic Suppositories - 10 or 20 Count

$64.95 - $99.95

Price includes FREE US 2nd Day Air shipping in an iced cooler. See description for details.

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PurO3’s probiotic suppositories are a multi-strain combination mixed with natural cocoa butter.

Our cocoa butter is certified organic and naturally contains vitamins, minerals, and bioflavonoids with antioxidant properties. This serves as a base for our combination of 18 strains of beneficial bacteria along with a prebiotic.

Each package contains your choice of 10 or 20 suppositories. This product is not ozonated. Each suppository contains 50.7 billion CFU (colony-forming units).

The benefit of using a suppository is that the total dosage of probiotics goes to the source of intestinal flora imbalance without having to be digested. When taken orally, anywhere from 1/2 to 3/4 or more of the strains do not make it past the stomach acids. Suppositories are a solution to this problem.

Probiotic suppositories are used to help reestablish gut flora, help diminish vaginal yeast infections and bacterial infections of BV (bacterial vaginosis), and may help prevent recurring urinary tract infections.

Probiotic Suppositories

More about probiotics

Our intestines contain a rich supply of blood vessels that actively exchange substances, and mucous membranes that harbor vast communities of functional bacteria. Numerous studies have examined the complex mechanisms of the beneficial effects of probiotics. Bacteria help create a protective lining on the walls of the intestine by stimulating the production of mucus and regulating adherence by certain bacteria. This helps support a proper balance of microbiota in the gut. Antimicrobial peptides, or bacteriocins, are produced by these bacteria and establish competitive exclusion of pathogenic strains.  

Each suppository contains 50.7 billion CFU (colony-forming units).

Note: This product is not ozonated.

Probiotic strains and Usage

  • L. casei – Study
  • L. acidophilus – Study
  • L. rhamnosus – Study
  • L. paracasei – Study
  • L. plantarum – Study
  • L. bulgaricus – see L. delbraekii below.
  • L. salivarius – Study
  • L. delbraekii – formally L. bulgaricus - Study | Study
  • L. helveticus – Study
  • L. brevis – Study
  • L. reuteri – Study

How to Use:

Use one suppository daily or as directed by your health care practitioner. To remove suppository, tear the plastic shell lengthwise beginning at the center perforation at the top (side view shown). Apply a lubricant if needed before insertion. Use as needed or as directed by your healthcare provider. For rectal use: Insert following a bowel movement. Insert past sphincter muscle. Sometimes after insertion you may have an urge to evacuate. Try to hold for 15 to 20 minutes if possible for best absorption of suppository. For vaginal use: Insert 2 to 4 inches when lying down, preferably at night. Remain in a flat position for at least 30 minutes for best absorption.


Keep refrigerated or frozen. Keep out of direct sunlight.

Important notes about shipping and order times

The $99 price includes FREE 2nd Day Air shipping in a special cooler to preserve the quality of the probiotics. These ship out Monday, Tuesday, and Wednesday only to ensure the package is not stuck in the heat on a weekend. Orders placed on Thursday-Sunday will ship the following Monday. International shipping is limited, so contact us for a shipping quote and custom order placement.

Note: If you order multiple products in one order, the order will ship together based on the timelines mentioned here. If you'd like other products to ship separately, please place separate orders.

Tracking numbers are provided with every order once shipped, and it is the customer's responsibility to be aware of when the parcel is delivered to prevent prolonged exposure outside. If you are in a highheat area, you'll want to keep track and grab your box as soon as possible when it arrives.